Detalhe da pesquisa
1.
Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Nature
; 623(7989): 1079-1085, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938782
2.
Efficacy of an oral lipid nanocrystal formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis.
Antimicrob Agents Chemother
; : e0154023, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687015
3.
Ibrexafungerp is efficacious in a neutropenic murine model of pulmonary mucormycosis as monotherapy and combined with liposomal amphotericin B.
Antimicrob Agents Chemother
; 68(5): e0154523, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557112
4.
The Combination Treatment of Fosmanogepix and Liposomal Amphotericin B Is Superior to Monotherapy in Treating Experimental Invasive Mold Infections.
Antimicrob Agents Chemother
; 66(7): e0038022, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35670592
5.
Combination treatment of liposomal amphotericin B and isavuconazole is synergistic in treating experimental mucormycosis.
J Antimicrob Chemother
; 76(10): 2636-2639, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34263306
6.
Selective inhibition of Rhizopus eumelanin biosynthesis by novel natural product scaffold-based designs caused significant inhibition of fungal pathogenesis.
Biochem J
; 477(13): 2489-2507, 2020 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32538426
7.
Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31818813
8.
Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32205345
9.
Preserving Vascular Integrity Protects Mice against Multidrug-Resistant Gram-Negative Bacterial Infection.
Antimicrob Agents Chemother
; 64(8)2020 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393494
10.
Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31685475
11.
APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis.
Antimicrob Agents Chemother
; 63(2)2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455236
12.
PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis.
J Clin Microbiol
; 56(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30068535
13.
Prophylaxis with Isavuconazole or Posaconazole Protects Immunosuppressed Mice from Pulmonary Mucormycosis.
Antimicrob Agents Chemother
; 61(5)2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28264840
14.
Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.
Antimicrob Agents Chemother
; 61(9)2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28652241
15.
Monotherapy or combination therapy of isavuconazole and micafungin for treating murine mucormycosis.
J Antimicrob Chemother
; 72(2): 462-466, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798213
16.
Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine.
PLoS Pathog
; 11(5): e1004842, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25974051
17.
Statin Concentrations Below the Minimum Inhibitory Concentration Attenuate the Virulence of Rhizopus oryzae.
J Infect Dis
; 214(1): 114-21, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26984141
18.
VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.
Antimicrob Agents Chemother
; 59(12): 7815-7, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26369977
19.
Isavuconazole therapy protects immunosuppressed mice from mucormycosis.
Antimicrob Agents Chemother
; 58(4): 2450-3, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24492363
20.
Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis.
Antimicrob Agents Chemother
; 57(7): 3340-7, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23650163